A client has been treated for 20 years with antipsychotic agents. The extended therapy of antipsychotic medications has caused the client to suffer from tardive dyskinesia. Which of the following centrally acting skeletal muscle relaxants possesses a structure that is similar to the inhibitory neurotransmitter GABA and will decrease the symptom of tardive dyskinesia?
1. Baclofen (Lioresal)
2. Tizanidine (Zanaflex)
3. Dantrolene (Dantrium)
4. Botulinum toxin type A
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