What is the difference between a statistically significant result and a clinically
What is the difference between a statistically significant result and a clinically or “real world” significant result? Give examples of both.
Hint
StatisticsStatistical significance without other information doesn’t have any relevant interpretation. It is not only possible but common to have clinically trivial results that are nonetheless statistically significant. Researchers differentiate between statistical significance and practical significance. A practical significance means that the treatment effect is important and large enough to ha...
Statistical significance without other information doesn’t have any relevant interpretation. It is not only possible but common to have clinically trivial results that are nonetheless statistically significant. Researchers differentiate between statistical significance and practical significance. A practical significance means that the treatment effect is important and large enough to have practical application. But a statistically significant result, either small or large, means that the observed effect is very unlikely to have occurred by chance. The presence of a ‘statistically significant’ effect does not necessarily mean the results are large enough for practical applications. For example, consider a study of a treatment for pain. Let it have a statistically significant effect, which may be tiny. Then it will reduce pain but very slightly. Thus is clinically significant.