A cohort study on red meat and Alzheimer’s Disease (AD) was conducted
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A cohort study on red meat and Alzheimer’s Disease (AD) was conducted

A cohort study on red meat and Alzheimer’s Disease (AD) was conducted, where educational achievement (EA) was considered both a potential confounder and a potential effect modifier. The counts data were stratified into high and low educational achievement as shown below in order to assess this issue.


a. Set up the 2x2 table for the research question for participants in the entire study.

b. Calculate the crude relative risk (RR) for participants in the entire study.

c. Calculate the relative risk (RR) for each of the 2 strata (i.e., in high and in low educational achievement households).

d. Calculate the pooled relative risk across strata (i.e., the educational achievement-adjusted association between red meat consumption and AD).

e. Is educational achievement a confounder in this study? Provide evidence to justify your answer.

f. Is educational achievement an effect modifier in this study? Provide evidence to justify your answer.

g. In directly reporting the association between red meat consumption and Alzheimer’s Disease based on this study, should you report the stratified results in part c, the pooled results obtained from part d, neither set of results, or both sets of results? Briefly explain.

Hint
StatisticsAlzheimer's disease (AD) is the most common form of dementia among older people. Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. AD begins slowly. It first involves the parts of the brain that control thought, memory and language....

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